Research Technician I at Massachusetts General Hospital
Department of Radiology, MGH
BA, Molecular Neuroscience and Genetics, Hampshire College
Jess performs histology and anatomical analyses on human brain tissue in order to examine the histology for improved brain mapping of neurotypical brains and those with aging and preclinical Alzheimer’s Disease pathology. The histochemistry protocols that Jess uses to microscopically examine brain regions are Nissl, Thioflavin S, and Gallyas myelin. She also uses Freeview to identify and manually label neuroanatomical structures on ex vivo human brain tissue. The labels are used as ground truth and training data to develop computational algorithms that model the structure, volume and surfaces of the human brain. These models are incorporated in the Freesurfer package.